Authorities said the accident occurred at about 6:30 p.m. in front of a home on North Conduit Avenue near 159th Street.
Police said Troy Smith of Rockaway Boulevard was behind the wheel of a 2010 Hyundai sedan traveling in the center lane on North Conduit Avenue at what was described as an unsafe speed.
Reportedly, the vehicle suddenly veered to the right, struck the curb and mounted the sidewalk, then turned on its side and smashed into a tree.
Officers from the 113th Precinct responded to the scene along with EMS units, who pronounced Smith dead at the location. No other injuries were reported.
An investigation by the NYPD Collision Investigation Squad is ongoing.